BDBM143293 US9682953, 4.A-3
SMILES Cc1nc(NC(=O)N2CCC[C@@]2(Cc2ccccc2)C(N)=O)sc1-c1ccnc(n1)C(C)(C)C
InChI Key InChIKey=IXPSVFXVBJDSFQ-GDNBJRDFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 143293
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human transmembrane domain deficient FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mi...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics
Curated by ChEMBL
Advinus Therapeutics
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of rat FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics
Curated by ChEMBL
Advinus Therapeutics
Curated by ChEMBL
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair