BDBM143321 US8940893, 6

SMILES Cn1c(Cc2ccccc2)ncc(-c2ccc(-c3nn(C4CC5(C4)CN(C5)C(=O)C=C)c4ncnc(N)c34)c(F)c2)c1=O

InChI Key InChIKey=VPAFMRVMSIUGST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143321   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM143321(US8940893, 6)
Affinity DataIC50:  0.850nMAssay Description:An HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent