BDBM143730 US8969341, 198

SMILES COc1nc(ncc1-n1nc2C(=O)N(C(c2c1C(C)C)c1ccc(Cl)c(F)c1)c1c[nH]c(=O)c(Cl)c1)N(C)C

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143730   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM143730(US8969341, 198)
Affinity DataIC50:  0.164nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
In DepthDetails US Patent