BDBM14482 2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-benzodiazol-3-ium::CA-24

SMILES Nc1[nH]c2ccc(NC(=O)c3cc4ccccc4cc3O)cc2[nH+]1

InChI Key InChIKey=LDVGDJNFYHOIPH-UHFFFAOYSA-O

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 14482   

TargetSerine protease hepsin(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi:  2.10E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi:  4.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi:  4.60E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi:  3.70E+4nM ΔG°:  -5.98kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi:  4.20E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi: >7.50E+4nM ΔG°: >-5.57kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi:  2.00E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi: >4.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi: >4.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed