BDBM148978 US8962646, B

SMILES CN1CC[C@]23CC(=O)CC[C@@]2(O)[C@H]1Cc1ccc(C(=O)NCCc2ccc(cc2)-c2ccccc2)c(O)c31

InChI Key InChIKey=SBFUBWXMWXCLMP-MBYALERHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 148978   

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148978(US8962646, B)
Affinity DataKi:  0.390nM ΔG°:  -12.8kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148978(US8962646, B)
Affinity DataKi:  0.710nM ΔG°:  -12.5kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148978(US8962646, B)
Affinity DataKi:  5.40nM ΔG°:  -11.3kcal/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent