BDBM149309 US8962674, CU520

SMILES Oc1ccc(CCC(=O)CC(=O)\C=C\c2ccc3ccn(Cc4ccccc4)c3c2)cc1

InChI Key InChIKey=CTXIJCIUFMEGDD-XNTDXEJSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149309   

TargetBeta-secretase 1(Homo sapiens (Human))
Tokyo Institute of Technology

US Patent
LigandPNGBDBM149309(US8962674, CU520)
Affinity DataIC50:  610nMpH: 4.5 T: 2°CAssay Description:Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...More data for this Ligand-Target Pair
In DepthDetails US Patent