BDBM149684 US8975267, 3
SMILES CCc1cccc(CC)c1NC(=O)c1c(C)n(C)c-2c1CCc1cnc(Nc3ccc(cc3OC)N3CCC(CC3)N3CCCC3)nc-21
InChI Key InChIKey=SWZFCGQEKUXWPZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 149684
Affinity DataIC50: 99nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair