BDBM149692 US8975267, 34
SMILES CSc1ncc2ccc3c(cn([C@@H]4CC[C@H](N)CC4)c3c2n1)C(N)=O
InChI Key InChIKey=FRANNCVVJFQWOT-TXEJJXNPSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 149692
Affinity DataIC50: 855nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5Assay Description:The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 3.0Assay Description:Specific peptide or protein substrates are trans-phosphorylated by their specific ser-thr or tyr kinase in the presence of ATP traced with 33P-gamma-...More data for this Ligand-Target Pair