BDBM149811 US8975415, RP92::US9242973, RP92

SMILES CCCC1Oc2ccc(cc2C2(COC(N)=N2)C11COC1)-c1cncc(c1)C#CC

InChI Key InChIKey=VKNCKYKSIFQAIK-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149811   

TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149811(US8975415, RP92 | US9242973, RP92)
Affinity DataKi:  87.9nM IC50:  124nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149811(US8975415, RP92 | US9242973, RP92)
Affinity DataIC50:  5.34E+3nMT: 2°CAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
In DepthDetails US Patent