BDBM150251 US8980932, 6c (DH310)

SMILES Cc1ncc(n1CCNC(=S)NCCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O

InChI Key InChIKey=DJCRWQDPBYNRKK-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 150251   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  2.90nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  2.90nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  8.30nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  8.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  8.5nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  8.5nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  79nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  79nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent