BDBM150300 US8987247, 1
SMILES Fc1ccc(cc1)-n1ccc2cc(ccc12)C(=O)N1CC(C1)N1CCN(CC1)C(=O)c1nccs1
InChI Key InChIKey=IVOACCSOISMVBL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 150300
Affinity DataIC50: <5nMAssay Description:All rate-based assays were performed in black 384-well polypropylene polymerase chain reaction (PCR) microplates (Abgene) in a total volume of 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:All rate-based assays were performed in black 384-well polypropylene polymerase chain reaction (PCR) microplates (Abgene) in a total volume of 30 ...More data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:The ThermoFluor (TF) assay is a 384-well microplate-based binding assay that measures thermal stability of proteins1,2. The experiments were carried ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydrationMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair