BDBM150614 US10238633, Example 288::US8987249, 288::US9713606, 288

SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc(o1)C(=O)N1CCOCC1

InChI Key InChIKey=QLIQIELZFMSNMZ-YWNPBTLJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150614   

TargetCathepsin K(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150614(US10238633, Example 288 | US8987249, 288 | US97136...)
Affinity DataIC50:  2.20E+3nMAssay Description:To activate the proenzyme, 5 μl procathepsin K were mixed with 1 ul activation buffer, and incubated at room temperature for 30 min.5 μL te...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150614(US10238633, Example 288 | US8987249, 288 | US97136...)
Affinity DataIC50:  2.30nMAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
In DepthDetails US Patent