BDBM151010 US8987257, 23

SMILES C[C@H]1COCCN1c1nc(nc2[nH]c(nc12)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=RLNRQOILVAIJJZ-DNQHLSNTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 151010   

LigandPNGBDBM151010(US8987257, 23)
Affinity DataIC50:  5.51E+3nMpH: 7.5 T: 2°CAssay Description:PI3K KinaseGlo assay: 50 mL of compound dilutions were dispensed onto black 384-well low volume Non Binding Styrene (NBS) plates (Costar Cat. No. NBS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM151010(US8987257, 23)
Affinity DataIC50:  14nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM151010(US8987257, 23)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:IC50s for mTOR interacting compounds were assessed using the FRAP1/mTOR TR-FRET tracer assay (Invitrogen by Life Technologies). FRAP1/mTOR (PV4753) a...More data for this Ligand-Target Pair
In DepthDetails US Patent