BDBM151011 US8987257, 24

SMILES C[C@H]1COCCN1c1nc(nc2[nH]c(nc12)-c1ccc2cc[nH]c2c1)N1CCOCC1

InChI Key InChIKey=QYSBWWZEGONCEB-DNQHLSNTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151011   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM151011(US8987257, 24)
Affinity DataIC50:  85nMpH: 7.5 T: 2°CAssay Description:IC50s for mTOR interacting compounds were assessed using the FRAP1/mTOR TR-FRET tracer assay (Invitrogen by Life Technologies). FRAP1/mTOR (PV4753) a...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM151011(US8987257, 24)
Affinity DataIC50:  8.54E+3nMpH: 7.5 T: 2°CAssay Description:PI3K KinaseGlo assay: 50 mL of compound dilutions were dispensed onto black 384-well low volume Non Binding Styrene (NBS) plates (Costar Cat. No. NBS...More data for this Ligand-Target Pair
In DepthDetails US Patent