BDBM152151 US8987474, HL1-056 (NSC-117199)
SMILES OS(=O)(=O)c1ccc2NC(=O)\C(=N/Nc3ccccc3[N+]([O-])=O)c2c1
InChI Key InChIKey=UNCWHIJFMMDYME-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 152151
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University of South Florida
US Patent
University of South Florida
US Patent
Affinity DataIC50: 4.73E+4nMAssay Description:NSC-87877 ranked among top 10% (175th) of the compounds with the best GLIDE scores for the docking to the human Shp2 PTP domain in our virtual screen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University of South Florida
US Patent
University of South Florida
US Patent
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University of South Florida
US Patent
University of South Florida
US Patent
Affinity DataIC50: 800nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University of South Florida
US Patent
University of South Florida
US Patent
Affinity DataIC50: 4.99E+3nMAssay Description:Inhibition of human GST-tagged Shp2 (205 to 593 residues) expressed Escherichia coli DH5alpha assessed as inhibition of PTP activity using DiFMUP as ...More data for this Ligand-Target Pair