BDBM15245 1-(3-Chlorophenyl)-3-[6-[1-(dimethylamino)propan-2-yloxy]-::3-(3-chlorophenyl)-1-(6-{[1-(dimethylamino)propan-2-yl]oxy}pyrazin-2-yl)urea::macrocyclic inhibitor 3
SMILES CC(CN(C)C)Oc1cncc(NC(=O)Nc2cccc(Cl)c2)n1
InChI Key InChIKey=OWNNCFPRNCLWHG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 15245
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...More data for this Ligand-Target Pair