BDBM152700 (S)-2-Amino-5-butyrimidamidopentanoic acid (9)::hDDAH inhibitor, 1b
SMILES CCCC(=N)NCCC[C@H](N)C(O)=O
InChI Key InChIKey=KRILJVOCVSUPMA-ZETCQYMHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 152700
Affinity DataKi: 8.61E+3nM IC50: 1.91E+4nMpH: 7.4Assay Description:The assay mixture contained L-arginine (10 μM), NADPH (100 μM), oxyhemoglobin (0.125 mg/mL), tetrahydrobiopterin (10 μM), and differen...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University
Christian-Albrechts-University
Affinity DataKi: 3.20E+4nM ΔG°: -6.37kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair