BDBM152700 (S)-2-Amino-5-butyrimidamidopentanoic acid (9)::hDDAH inhibitor, 1b

SMILES CCCC(=N)NCCC[C@H](N)C(O)=O

InChI Key InChIKey=KRILJVOCVSUPMA-ZETCQYMHSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152700   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM152700((S)-2-Amino-5-butyrimidamidopentanoic acid (9) | h...)
Affinity DataKi:  8.61E+3nM IC50:  1.91E+4nMpH: 7.4Assay Description:The assay mixture contained L-arginine (10 μM), NADPH (100 μM), oxyhemoglobin (0.125 mg/mL), tetrahydrobiopterin (10 μM), and differen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University

LigandPNGBDBM152700((S)-2-Amino-5-butyrimidamidopentanoic acid (9) | h...)
Affinity DataKi:  3.20E+4nM ΔG°:  -6.37kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed