BDBM153658 US8999998, 41
SMILES Cc1cc(NC(=O)c2cnn3cccnc23)n(n1)-c1cc(Cl)ccc1Cl
InChI Key InChIKey=YHYZLBBGBXJVRK-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 153658
Affinity DataKi: 3.30nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 35.1nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 73.9nMpH: 7.2Assay Description:The activity of the isolated JAK3 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Leu-Pro-Leu-Asp-Lys-Asp-Ty...More data for this Ligand-Target Pair
Affinity DataKi: 104nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair