BDBM153663 US8999998, 109
SMILES COc1ccc(Cl)cc1-c1c(NC(=O)c2cnn3cccnc23)cnn1CCO
InChI Key InChIKey=JWMNWMLDJKHWSK-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 153663
Affinity DataKi: 1nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 18nMpH: 7.2Assay Description:The activity of the isolated JAK3 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Leu-Pro-Leu-Asp-Lys-Asp-Ty...More data for this Ligand-Target Pair