BDBM153675 US8999998, 395
SMILES O=C(Nc1c[nH]nc1N1CCC(CC1)C#N)c1cnn2cccnc12
InChI Key InChIKey=SDGQVTSJYRDVBO-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 153675
Affinity DataKi: 31.3nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 176nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 230nMpH: 7.2Assay Description:The activity of the isolated JAK1, JAK2 or TYK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-Ala-Leu-...More data for this Ligand-Target Pair
Affinity DataKi: 390nMpH: 7.2Assay Description:The activity of the isolated JAK3 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Leu-Pro-Leu-Asp-Lys-Asp-Ty...More data for this Ligand-Target Pair