BDBM153689 US10507215, Compound 6::US9000015, 6

SMILES Cc1cc(cc(=O)[nH]1)-c1ccc(CNC(=O)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=LWYWZWJVXJWUFS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 153689   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM153689(US10507215, Compound 6 | US9000015, 6)
Affinity DataIC50: >1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM153689(US10507215, Compound 6 | US9000015, 6)
Affinity DataIC50: >1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM153689(US10507215, Compound 6 | US9000015, 6)
Affinity DataIC50: >1.30E+5nMAssay Description:MAO assays included lumnuogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with esterase. Standard MAO reacti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Amygdala Neurosciences

US Patent
LigandPNGBDBM153689(US10507215, Compound 6 | US9000015, 6)
Affinity DataIC50:  1.11E+3nMAssay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM153689(US10507215, Compound 6 | US9000015, 6)
Affinity DataIC50: >1.30E+5nMAssay Description:MAO assays included lumnuogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with esterase. Standard MAO reacti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Amygdala Neurosciences

US Patent
LigandPNGBDBM153689(US10507215, Compound 6 | US9000015, 6)
Affinity DataIC50:  1.11E+3nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails US Patent