BDBM153768 US8999981, A13::US8999981, A14

SMILES CC1(C)N(Cc2c(NC(=O)c3ccc4ccccc4n3)n[nH]c12)C(=O)N1C[C@@H]2CCCN2C[C@@H]1Cc1ccccc1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153768   

TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM153768(US8999981, A13 | US8999981, A14)
Affinity DataKi:  16.1nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM153768(US8999981, A13 | US8999981, A14)
Affinity DataKi:  27.7nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In DepthDetails US Patent