BDBM154387 US9012443, 427

SMILES COc1cc(ccc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccc(F)cn1)C(F)(F)F

InChI Key InChIKey=JJDMPIUFRKPKLP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154387   

TargetSepiapterin reductase(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM154387(US9012443, 427)Copy SMILESCopy InChI

Affinity DataIC50:  1.78E+3nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent

LigandBDBM154387(US9012443, 427)Copy SMILESCopy InChI

Affinity DataIC50:  4.42E+3nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI