BDBM156389 US9018381, 12::US9248140, 12

SMILES CCN(CCO)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)[C@@H](N)c1ccccc1-c1ccc(Cl)cc1

InChI Key InChIKey=BUTLNWRLMGMMFQ-CAZXVXRPSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156389   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM156389(US9018381, 12 | US9248140, 12)
Affinity DataIC50:  3nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2 [1-204](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM156389(US9018381, 12 | US9248140, 12)
Affinity DataIC50:  3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1 [1-209](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM156389(US9018381, 12 | US9248140, 12)
Affinity DataIC50:  3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM156389(US9018381, 12 | US9248140, 12)
Affinity DataIC50:  3nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails US Patent