BDBM157232 US9023865, 78
SMILES Cc1cc(ccn1)-c1n[nH]c2cc(NC(=O)NC3CCc4ccccc34)ncc12
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 157232
Affinity DataIC50: 5.39nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human ERK2 preincubated for 15 mins followed by addition of IMAP peptide substrate and ATP measured after 60 mins by IMAP-FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human ERK2 preincubated for 15 mins followed by addition of IMAP peptide substrate and ATP measured after 60 mins by IMAP-FP assayMore data for this Ligand-Target Pair