BDBM15928 Aminopyridine-Based Inhibitor 6g::N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(3-chlorophenyl)acetamide

SMILES CCOc1nc(NC(=O)Cc2cccc(Cl)c2)cc(N)c1C#N

InChI Key InChIKey=ICCHKYUWVDXHIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15928   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15928(Aminopyridine-Based Inhibitor 6g | N-(4-Amino-5-cy...)
Affinity DataIC50:  900nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15928(Aminopyridine-Based Inhibitor 6g | N-(4-Amino-5-cy...)
Affinity DataIC50:  300nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed