BDBM159346 US9034899, 39::US9604960, 39

SMILES Fc1cc2C(CNCc2cc1-c1ccc2ncnn2c1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WNADNMZKSSOJHJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 159346   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM159346(US9034899, 39 | US9604960, 39)
Affinity DataIC50:  14.1nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM159346(US9034899, 39 | US9604960, 39)
Affinity DataIC50:  83.2nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM159346(US9034899, 39 | US9604960, 39)
Affinity DataIC50:  70nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM159346(US9034899, 39 | US9604960, 39)
Affinity DataIC50:  14nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM159346(US9034899, 39 | US9604960, 39)
Affinity DataIC50:  83nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM159346(US9034899, 39 | US9604960, 39)
Affinity DataIC50:  70.4nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent