BDBM159358 US9034907, 11

SMILES Cc1cncn1CCCn1c(=S)[nH]c2sc3CCCCCCc3c2c1=O

InChI Key InChIKey=RUXPVUOUZBSEBR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159358   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM159358(US9034907, 11)
Affinity DataKi:  28.5nM ΔG°:  -10.5kcal/mole IC50:  170nMpH: 8.0 T: 2°CAssay Description:Fluorometric Assays: All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30 C. QC activity was eval...More data for this Ligand-Target Pair
In DepthDetails US Patent