BDBM159378 US9034907, 33

SMILES CCc1c(C)sc2[nH]c(=S)n(CCCn3ccnc3)c(=O)c12

InChI Key InChIKey=JTHRXQCJEJVKQE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159378   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM159378(US9034907, 33)
Affinity DataKi:  1.12E+3nM ΔG°:  -8.25kcal/mole IC50:  1.10E+4nMpH: 8.0 T: 2°CAssay Description:Fluorometric Assays: All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30 C. QC activity was eval...More data for this Ligand-Target Pair
In DepthDetails US Patent