BDBM15940 Aminopyridine-Based Inhibitor 6t::N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamide

SMILES CCOc1nc(NC(=O)Cc2cc(OC)c(Br)cc2OC)cc(N)c1C#N

InChI Key InChIKey=GKODDLYLEKSDJL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15940   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15940(Aminopyridine-Based Inhibitor 6t | N-(4-Amino-5-cy...)
Affinity DataIC50:  160nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15940(Aminopyridine-Based Inhibitor 6t | N-(4-Amino-5-cy...)
Affinity DataIC50:  77nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair