BDBM15952 1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)methyl]-piperidine-4-carboxylic Acid Butylamide::1-{[(4-amino-5-cyano-6-ethoxypyridin-2-yl)carbamoyl]methyl}-N-butylpiperidine-4-carboxamide::Aminopyridine-Based Inhibitor 33

SMILES CCCCNC(=O)C1CCN(CC(=O)Nc2cc(N)c(C#N)c(OCC)n2)CC1

InChI Key InChIKey=DWLWDAIUYUOIEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15952   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15952(1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...)
Affinity DataIC50:  180nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15952(1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...)
Affinity DataIC50:  69nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed