BDBM161451 US10124003, Ex. Compound 64::US10835536, Ex. Comp 64::US10894048, Ex Comp 64::US9108973, 64

SMILES COc1cc(OC)cc(c1)C#Cc1cn(C2CCN(CC2)C(=O)C=C)c2ncnc(N)c12

InChI Key InChIKey=FXNCSORTIDLEQF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161451   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161451(US10124003, Ex. Compound 64 | US10835536, Ex. Comp...)
Affinity DataIC50:  7.90nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161451(US10124003, Ex. Compound 64 | US10835536, Ex. Comp...)
Affinity DataIC50:  7.90nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161451(US10124003, Ex. Compound 64 | US10835536, Ex. Comp...)
Affinity DataIC50:  7.90nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161451(US10124003, Ex. Compound 64 | US10835536, Ex. Comp...)
Affinity DataIC50:  7.90nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent