BDBM161461 US10124003, Ref. Ex. Compound 2::US10835536, Ref. Ex. Comp 2::US10894048, Ref. Ex Comp. 2::US9108973, Ref 2

SMILES Nc1nccn2c(nc(C#Cc3ccccc3)c12)C1CCC1

InChI Key InChIKey=AANYNPDCJWMSSH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161461   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161461(US10124003, Ref. Ex. Compound 2 | US10835536, Ref....)
Affinity DataIC50:  270nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161461(US10124003, Ref. Ex. Compound 2 | US10835536, Ref....)
Affinity DataIC50:  270nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161461(US10124003, Ref. Ex. Compound 2 | US10835536, Ref....)
Affinity DataIC50:  270nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161461(US10124003, Ref. Ex. Compound 2 | US10835536, Ref....)
Affinity DataIC50:  270nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent