BDBM16180 (2S)-2-{[4-({[(2S)-1-cyclohexyl-3-(ethylsulfanyl)propan-2-yl]amino}methyl)-2-(2-methylphenyl)phenyl]formamido}-4-(methylsulfanyl)butanoic acid::A197574::CHEMBL344100::N-({5-[({(1S)-2-cyclohexyl-1-[(ethylsulfanyl)methyl]ethyl}amino)methyl]-2 -methylbiphenyl-2-yl}carbonyl)-L-methionine

SMILES CCSC[C@H](CC1CCCCC1)NCc1ccc(C(=O)N[C@@H](CCSC)C(O)=O)c(c1)-c1ccccc1C

InChI Key InChIKey=SAVLZOMOKUOGAK-SVEHJYQDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16180   

LigandPNGBDBM16180((2S)-2-{[4-({[(2S)-1-cyclohexyl-3-(ethylsulfanyl)p...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibitory activity against Farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent RNA helicase RhlE(Plasmodium falciparum (malaria parasite P. falcipa...)
University of Washington At Seattle

LigandPNGBDBM16180((2S)-2-{[4-({[(2S)-1-cyclohexyl-3-(ethylsulfanyl)p...)
Affinity DataIC50:  5nMAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed