BDBM162629 US9687479, 109 3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-[(2,3-dihydro-1,4-benzodioxin-5-yl)carbonyl]-1H-pyrazol-3-yl)-1-(2-methoxyethyl)-1,2-dihydropyridin-2-one

SMILES COCCn1cccc(-c2cc(NCc3ccc(Cl)s3)n(n2)C(=O)c2cccc3OCCOc23)c1=O

InChI Key InChIKey=QIPXCTVJXJLOKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162629   

TargetPlasma kallikrein(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM162629(US9687479, 109 3-(5-[(5-chlorothiophen-2-yl)methyl...)
Affinity DataIC50:  5.50E+3nMpH: 7.4 T: 2°CAssay Description:Human KLKB1 protein was obtained from Enzyme Research Labs. The chromogenic substrate S-2302 was obtained from DiaPharma. KLKB1 was assayed in buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Verseon

US Patent
LigandPNGBDBM162629(US9687479, 109 3-(5-[(5-chlorothiophen-2-yl)methyl...)
Affinity DataIC50: <100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent