BDBM162865 US9056843, 156
SMILES C[C@H](CN(C)Cc1ccccc1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F
InChI Key InChIKey=RESDVUQVZOJNSO-CQSZACIVSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 162865
Affinity DataIC50: 2.90E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC1. Human recombinant full length HDAC1 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC8 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC6. Human recombinant full length HDAC6 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of HDAC class 1 in human HT-29 cells using Boc-Lys-Ac as substrate incubated for 3 hrs by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human HDAC4 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human HDAC5 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human HDAC7 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC10 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC11 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC1 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC2 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC3 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: >600nMAssay Description:Inhibition of recombinant human HDAC6 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair