BDBM16306 2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximidamide::2-pyridin-2-yl-1H-benzimidazole-6-carboximidamide::APD-4::CHEMBL381148
SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccccn1
InChI Key InChIKey=RVIFTTGMSLOWED-UHFFFAOYSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 16306
Affinity DataKi: 27nMAssay Description:Binding affinity to FXa in presence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 720nMAssay Description:Binding affinity to thrombin in presence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 721nM ΔG°: -8.29kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Binding affinity to FVIIa in presence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -7.82kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 1.93E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 2.09E+4nM ΔG°: -6.32kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 4.56E+4nMAssay Description:Binding affinity to FXa in absence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Binding affinity to thrombin in absence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 8.15E+4nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 1.01E+5nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair