BDBM16307 2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carboximidamide::2-(pyridin-2-ylmethyl)-1H-benzimidazole-6-carboximidamide::APD-5::CHEMBL204126
SMILES NC(=N)c1ccc2nc(Cc3ccccn3)[nH]c2c1
InChI Key InChIKey=MHSMXTLGYPLSJM-UHFFFAOYSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 16307
Affinity DataKi: 60nMAssay Description:Binding affinity to FXa in presence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 310nM ΔG°: -8.78kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+4nM ΔG°: -6.72kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+4nMAssay Description:Binding affinity to thrombin in presence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Binding affinity to FVIIa in presence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 1.36E+5nM ΔG°: -5.22kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: >1.50E+5nMAssay Description:Binding affinity to FXa in absence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: >1.50E+5nMAssay Description:Binding affinity to thrombin in absence of Zn2+More data for this Ligand-Target Pair
Affinity DataKi: 3.58E+5nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair