BDBM164272 US9669029, 22 1-{2-[2-(5,7-Dimethyl-imidazo[1,2-a]pyrimidin-2-yl)-ethyl]-4-thiophen-2-yl-imidazol-1-yl}-3-methoxy-propan-2-ol

SMILES CCOCC(O)Cn1cc(nc1CCc1cn2c(C)cc(C)nc2n1)-c1cccs1

InChI Key InChIKey=VLILOWCQERIRFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164272   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM164272(US9669029, 22 1-{2-[2-(5,7-Dimethyl-imidazo[1,2-a]...)
Affinity DataIC50:  7.90nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent