BDBM164372 US9669029, 75 [((S)-2-Hydroxy-3-{2-[2-(5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-ethyl]-4-thiophen-2-yl-imidazol-1-yl}-propyl)-methyl-amino]-acetonitrile

SMILES CN(CC#N)C[C@H](O)Cn1cc(nc1CCC1=NN2C(N1)C=CC=C2C)-c1cccs1

InChI Key InChIKey=GOEJGMHYTVPBPZ-LBOXEOMUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164372   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM164372(US9669029, 75 [((S)-2-Hydroxy-3-{2-[2-(5-methyl-[1...)
Affinity DataIC50:  8.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent