BDBM164465 US9066954, 279

SMILES COc1ccc2c(OCc3nnc4ccc(cn34)-c3ncc(C)s3)ccnc2c1

InChI Key InChIKey=OBEXMXPKTBIHED-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164465   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM164465(US9066954, 279)
Affinity DataKi:  19.7nM ΔG°:  -10.6kcal/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent