BDBM16455 6-(1-benzothiophene-2-sulfonyl)-2,3-dihydropyridazin-3-one::Heterocyclic Sulfonylpyridazinone, 19w::benzothiophene, 21

SMILES O=c1ccc(n[nH]1)S(=O)(=O)c1cc2ccccc2s1

InChI Key InChIKey=HUXFTBDIUUZFRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16455   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16455(6-(1-benzothiophene-2-sulfonyl)-2,3-dihydropyridaz...)
Affinity DataIC50:  150nMpH: 7.0 T: 2°CAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16455(6-(1-benzothiophene-2-sulfonyl)-2,3-dihydropyridaz...)
Affinity DataIC50:  180nMAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed