BDBM165194 4‐Chloro‐7‐nitro‐3‐[(5‐phenylpentyl)oxy]isochromen‐1‐one (21)
SMILES [O-][N+](=O)c1ccc2c(Cl)c(OCCCCCc3ccccc3)oc(=O)c2c1
InChI Key InChIKey=VKSNRCDTOIDGQI-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 165194
TargetRhomboid domain-containing protein(Aquifex aeolicus (Aquificales))
Technische Universität München
Technische Universität München
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid domain-containing protein(Pyrococcus horikoshii (Euryarchaeotes))
Technische Universität München
Technische Universität München
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München
Technische Universität München
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München
Technische Universität München
Affinity DataIC50: 4.60E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
TargetRhomboid protease GluP [F193S,L370F,L379S,R499W](Bacillus subtilis (Firmicutes))
Technische Universität München
Technische Universität München
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair