BDBM16733 4-[1-(5-Amino)-pentyl]-1-{4-(phenyl)-2-[(naphthalene-1-carbonyl)-amino]-phenyl}-piperazine::N-{2-[4-(5-aminopentyl)piperazin-1-yl]-5-phenylphenyl}naphthalene-1-carboxamide::Naphthyl Compound, 5d

SMILES NCCCCCN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc2ccccc12)-c1ccccc1

InChI Key InChIKey=PZHWVACDFBHKQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16733   

TargetBeta-secretase 1(Homo sapiens (Human))
Applied Science University

Curated by ChEMBL
LigandPNGBDBM16733(4-[1-(5-Amino)-pentyl]-1-{4-(phenyl)-2-[(naphthale...)
Affinity DataIC50:  68nMAssay Description:Inhibition of BACE1 after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Applied Science University

Curated by ChEMBL
LigandPNGBDBM16733(4-[1-(5-Amino)-pentyl]-1-{4-(phenyl)-2-[(naphthale...)
Affinity DataIC50:  68nMpH: 7.5 T: 2°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed