BDBM167419 US9073893, 18
SMILES Cn1n(C2CCN(CC2)C2CCC2)c(=O)c2c(cccc12)C(N)=O
InChI Key InChIKey=QNLAVJXTBVYHBB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 167419
Affinity DataIC50: 23nMT: 2°CAssay Description:Cellular activity of PARP-1 inhibitors was assessed by measuring the inhibition of the hydrogen peroxide induced PAR formation in HeLa cells (ECACC)....More data for this Ligand-Target Pair
Affinity DataKd: <10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair