BDBM169989 US9073940, 339
SMILES Fc1cccc2-c3c(CS(=O)(=O)c12)c(nn3-c1ccc(CN2CCOCC2)cc1)C(=O)N1CCOCC1
InChI Key InChIKey=NFHSJYKXENYICE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 169989
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta/gamma isoform(Homo sapiens (Human))
Merck Serono
US Patent
Merck Serono
US Patent
Affinity DataIC50: 347nMAssay Description:The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
South China University of Technology
Curated by ChEMBL
South China University of Technology
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of choline acetyltransferase (ChAT) activityMore data for this Ligand-Target Pair