BDBM169989 US9073940, 339

SMILES Fc1cccc2-c3c(CS(=O)(=O)c12)c(nn3-c1ccc(CN2CCOCC2)cc1)C(=O)N1CCOCC1

InChI Key InChIKey=NFHSJYKXENYICE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 169989   

LigandPNGBDBM169989(US9073940, 339)
Affinity DataIC50:  347nMAssay Description:The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM169989(US9073940, 339)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM169989(US9073940, 339)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM169989(US9073940, 339)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM169989(US9073940, 339)
Affinity DataIC50:  140nMAssay Description:Inhibition of choline acetyltransferase (ChAT) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed