BDBM17004 BX-517::Indolinone based inhibitor, 4i::[(3Z)-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylidene]-2,3-dihydro-1H-indol-5-yl]urea

SMILES C\C(=C1\C(=O)Nc2ccc(NC(N)=O)cc12)c1ccc[nH]1

InChI Key InChIKey=DFURSNCTQGJRRX-JYRVWZFOSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17004   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM17004(BX-517 | Indolinone based inhibitor, 4i | [(3Z)-2-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair