BDBM170116 US9073940, 474
SMILES COC1CCN(CCN2CCC[C@@H](C2)n2nc(C(=O)N3CCOCC3)c3CS(=O)(=O)c4cc(F)ccc4-c23)CC1
InChI Key InChIKey=FGJSGEOFFFKFLV-NRFANRHFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 170116
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta/gamma isoform(Homo sapiens (Human))
Merck Serono
US Patent
Merck Serono
US Patent
Affinity DataIC50: 13nMAssay Description:The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...More data for this Ligand-Target Pair