BDBM170440 US9085531, 40
SMILES CN1CC(c2ccc3sccc3c2)c2ccccc2C1
InChI Key InChIKey=MHFUBIDIXOMIAL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 170440
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 1.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 1.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 4nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 4nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataIC50: 69nMAssay Description:Displacement of [3H]Citolapram from human SERT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Displacement of [3H]WIN 35,428 from human DAT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataIC50: 350nMAssay Description:Displacement of [3H]Nisoxetine from human NET expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-RTI-55 from recombinant SERT (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]-RTI-55 from recombinant DAT (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]-RTI-55 from recombinant NET (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair