BDBM170453 US9085531, 100

SMILES CN1CC(c2ccc3sccc3c2)c2ccc(cc2C1)N1CCOCC1

InChI Key InChIKey=QLQQUDCJVQOCBW-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 170453   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170453(US9085531, 100)
Affinity DataKi:  7.10nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170453(US9085531, 100)
Affinity DataKi:  7.60nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170453(US9085531, 100)
Affinity DataKi:  53.4nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170453(US9085531, 100)
Affinity DataIC50:  93nMAssay Description:Displacement of [125I]-RTI-55 from recombinant NET (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170453(US9085531, 100)
Affinity DataIC50:  140nMAssay Description:Displacement of [125I]-RTI-55 from recombinant DAT (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM170453(US9085531, 100)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125I]-RTI-55 from recombinant SERT (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed